The wife of a policeman is brought in after a reaction to the ecstasy she took to relieve the symptoms of Parkinson’s disease; though Lara wants to report the husband, Harry decides to let it go. Roxy gets involved with a patient who has an inoperable brain tumour. Colette challenges an elusive Simon following their tryst at the staff Christmas party, to find he thinks it was a mistake and they should forget it. But she tells Comfort she thinks her marriage to Josh is over.

| Eddie Vincent | Philip Martin Brown | |
| John Adsett | Andrew Bicknall | |
| Diane Adsett | Fiona Welburn | |
| Jane Winter | N’Deaye Baa-Clements | |
| Andy Wells | Seb Castang | |
| Glen | Jason Nicoli | |
| Pete | Grahame Fox | |
| Karen Howe | Nicola King | |
| Ray Howe | David Delve | |
| Sarah Howe | Chelsea Whatley | |
| PC McCormack | Nicholas Tizzard | |
| Ms Marston | Lucinda Curtis | |
| Billy | Jeremt David |